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| カタログ番号 | HF800022 |
|---|---|
| 説明 |
Recombinant Human SVIL Protein, N-His (HF800022) expressed in E. coli, spanning Met1444-Lys1678. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | O95425 |
| タンパク質長 | Met1444-Lys1678 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 28.99 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | Archvillin, SVIL, Supervillin, p205/p250 |
| 背景 | Supervillin is a ~247 kDa protein. Forms a high-affinity link between the actin cytoskeleton and the membrane. Is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. 1. Oh, SW. et al. (2003) Journal of cell science 116, 2261-75. PMID: 12711699 2. Crowley, JL. et al. (2009) Molecular biology of the cell 20, 948-62. PMID: 19109420 3. Laurent, B. et al. (2015) Molecular cell 57, 957-970. PMID: 25684206 |
| 注意事項 | For research use only |
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