Human TJP3 Recombinant Protein (N-His) (HC970012)

Name: Human TJP3 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC970012
Price: 211 USD
Availability: InStock

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100ug
1mg

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Каталожный номер	HC970012
Описание	Recombinant Human TJP3 Protein, N-His (HC970012) expressed in E. coli, spanning Ser378-Asp776. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	O95049
Длина белка	Ser378-Asp776
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	46.98 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	TJP3, Tight junction protein 3, Tight junction protein ZO-3, ZO3, Zona occludens protein 3, Zonula occludens protein 3
Фон	Tight junction protein ZO-3 is a ~101 kDa protein. TJP1, TJP2, and TJP3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton. The tight junction acts to limit movement of substances through the paracellular space and as a boundary between the compositionally distinct apical and basolateral plasma membrane domains of epithelial and endothelial cells. Binds and recruits PATJ to tight junctions where it connects and stabilizes apical and lateral components of tight junctions. Promotes cell-cycle progression through the sequestration of cyclin D1 (CCND1) at tight junctions during mitosis which prevents CCND1 degradation during M-phase and enables S-phase transition. With TJP1 and TJP2, participates in the junctional retention and stability of the transcription factor DBPA, but is not involved in its shuttling to the nucleus. 1. Michel, D. et al. (2005) Journal of cell science 118, 4049-57. PMID: 16129888 2. Capaldo, CT. et al. (2011) Molecular biology of the cell 22, 1677-85. PMID: 21411630
Примечание	For research use only

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Даташит

Human TJP3 Recombinant Protein (N-His).pdf

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C₁ (Stock Conc.)

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