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Human TMED10 Recombinant Protein (N-His) (HW693022)

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Vista general
Número de catálogoHW693022
Descripción
Recombinant Human TMED10 Protein, N-His (HW693022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresiónE. coli
Número de accesoP49755
Longitud de proteínaIle32-Arg185
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesHomo sapiens (Human)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos21 kDa transmembrane-trafficking protein, Protein TMED10, S31I125, S31III125, TMED10, TMP21, Tmp-21-I, Transmembrane emp24 domain-containing protein 10, Transmembrane protein Tmp21, p23, p24 family protein delta-1, p24delta, p24delta1
Fondo

Transmembrane emp24 domain-containing protein 10 is a ~24 kDa protein. Cargo receptor involved in protein vesicular trafficking and quality control in the endoplasmic reticulum (ER) and Golgi. The p24 protein family is a group of transmembrane proteins that bind coat protein complex I/COPI and coat protein complex II/COPII involved in vesicular trafficking between the membranes. Acts at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and involved in vesicle coat formation at the cytoplasmic side. Mainly functions in the early secretory pathway and cycles between the ER, ER-Golgi intermediate compartment (ERGIC) and Golgi, mediating cargo transport through COPI and COPII-coated vesicles. In COPII vesicle-mediated anterograde transport, involved in the transport of GPI-anchored proteins by acting together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER.

1. Bremser, M. et al. (1999) Cell 96, 495-506. PMID: 10052452
2. Gommel, DU. et al. (2001) The EMBO journal 20, 6751-60. PMID: 11726511
3. Chen, F. et al. (2006) Nature 440, 1208-12. PMID: 16641999
4. Vetrivel, KS. et al. (2007) Molecular neurodegeneration 2, 4. PMID: 17288597
5. Luo, R. et al. (2009) Cellular signalling 21, 1169-79. PMID: 19296914
6. Bonnon, C. et al. (2010) Journal of cell science 123, 1705-15. PMID: 20427317
7. Luo, W. et al. (2011) Journal of neurochemistry 117, 71-81. PMID: 21219331
8. Nagae, M. et al. (2016) Journal of molecular biology 428, 4087-4099. PMID: 27569046
Nota For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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