Human TSPAN4 Recombinant Protein (N-His) (HD423012)

Name: Human TSPAN4 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD423012
Price: 211 USD
Availability: InStock

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1mg

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Обзор

Каталожный номер	HD423012
Описание	Recombinant Human TSPAN4 Protein, N-His (HD423012) expressed in E. coli, spanning Tyr107-Asn201. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	O14817
Длина белка	Tyr107-Asn201
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	13.23 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	NAG-2, NAG2, Novel antigen 2, TM4SF7, TSPAN4, Tetraspanin-4, Transmembrane 4 superfamily member 7, Tspan-4
Фон	Tetraspanin-4 is a ~26 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Plays an essential role in migrasome formation and migration on retracting fibers at the rear end of migrating cells. Migrasomes are cellular organelles that form as large vesicle-like structures on retraction fibers of migrating cells. Mechanistically, acts as a membrane curvature sensor and participates in stabilizing the migrasome structure in a late stage of biogenesis. May also play a regulatory role for the histamine H4 receptor/HRH4 without affecting histamine binding to HRH4 or signaling. 1. Huang, Y. et al. (2019) Nature cell biology 21, 991-1002. PMID: 31371828 2. Dharan, R. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119, e2208993119. PMID: 36252000 3. Dharan, R. et al. (2023) Nature communications 14, 1037. PMID: 36823145 4. Ma, X. et al. (2021) Biomolecules 11. PMID: 34439793
Примечание	For research use only

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Даташит

Human TSPAN4 Recombinant Protein (N-His).pdf

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