Human TUT7 Recombinant Protein (N-His) (HC200012)

Name: Human TUT7 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC200012
Price: 211 USD
Availability: InStock

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Número de catálogo	HC200012
Descripción	Recombinant Human TUT7 Protein, N-His (HC200012) expressed in E. coli, spanning Lys996-Arg1379. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q5VYS8
Longitud de proteína	Lys996-Arg1379
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	46.91 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	EC:2.7.7.52, HS2, KIAA1711, TUT7, TUTase 7, Terminal uridylyltransferase 7, ZCCHC6, Zinc finger CCHC domain-containing protein 6
Fondo	Terminal uridylyltransferase 7 is a ~171 kDa protein. Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay. Essential for both oocyte maturation and fertility. Through 3' terminal uridylation of mRNA, sculpts, with TUT7, the maternal transcriptome by eliminating transcripts during oocyte growth. Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets. Also functions as an integral regulator of microRNA biogenesiS using 3 different uridylation mechanisms. 1. Heo, I. et al. (2009) Cell 138, 696-708. PMID: 19703396 2. Lim, J. et al. (2014) Cell 159, 1365-76. PMID: 25480299 3. Kim, B. et al. (2015) The EMBO journal 34, 1801-15. PMID: 25979828 4. Thornton, JE. et al. (2012) RNA (New York, N.Y.) 18, 1875-85. PMID: 22898984 5. Faehnle, CR. et al. (2017) Nature structural & molecular biology 24, 658-665. PMID: 28671666 6. Mullen, TE. et al. (2008) Genes & development 22, 50-65. PMID: 18172165
Nota	For research use only

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Datasheet

Human TUT7 Recombinant Protein (N-His).pdf

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