Human USP5 Recombinant Protein (N-His) (HC178012)

Name: Human USP5 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC178012
Price: 211 USD
Availability: InStock

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100ug
1mg

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Каталожный номер	HC178012
Описание	Recombinant Human USP5 Protein, N-His (HC178012) expressed in E. coli, spanning Lys163-Lys291. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	P45974
Длина белка	Lys163-Lys291
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	16.87 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Deubiquitinating enzyme 5, EC:3.4.19.12, ISOT, Isopeptidase T, USP5, Ubiquitin carboxyl-terminal hydrolase 5, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5
Фон	Ubiquitin carboxyl-terminal hydrolase 5 is a ~95 kDa protein. Deubiquitinating enzyme that participates in a wide range of cellular processes by specifically cleaving isopeptide bonds between ubiquitin and substrate proteins or ubiquitin itself. Affects thereby important cellular signaling pathways such as NF-kappa-B, Wnt/beta-catenin, and cytokine production by regulating ubiquitin-dependent protein degradation. Participates in the activation of the Wnt signaling pathway by promoting FOXM1 deubiquitination and stabilization that induces the recruitment of beta-catenin to Wnt target gene promoter. Regulates the assembly and disassembly of heat-induced stress granules by mediating the hydrolysis of unanchored ubiquitin chains. Promotes lipopolysaccharide-induced apoptosis and inflammatory response by stabilizing the TXNIP protein. 1. Chen, Y. et al. (2016) The EMBO journal 35, 668-84. PMID: 26912724 2. Xie, X. et al. (2018) Journal of cell science 131. PMID: 29567855 3. Shi, S. et al. (2023) Hepatology communications 7. PMID: 37534934 4. Xiao, X. et al. (2023) Nature communications 14, 2859. PMID: 37208329 5. Pai, YL. et al. (2023) Cell death & disease 14, 540. PMID: 37607937 6. Qiao, Z. et al. (2025) PLoS pathogens 21, e1012843. PMID: 39761299 7. Mao, C. et al. (2024) The Journal of biological chemistry 300, 107592. PMID: 39032648 8. Shao, N. et al. (2025) Nature communications 16, 1313. PMID: 39900921
Примечание	For research use only

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Даташит

Human USP5 Recombinant Protein (N-His).pdf

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Formula

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