Human YEATS4 Recombinant Protein (N-GST) (HF502012)

Name: Human YEATS4 Recombinant Protein (N-GST)
Brand: abinScience
SKU: HF502012
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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SDS

Vista general

Número de catálogo	HF502012
Descripción	Recombinant Human YEATS4 Protein, N-GST (HF502012) expressed in E. coli, spanning Met1-Ile227. Purity: >90% by SDS-PAGE. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	O95619
Longitud de proteína	Met1-Ile227
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	53.31 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Gas41, Glioma-amplified sequence 41, YEATS4, GAS41, NuBI1, NuBI-1, YEATS domain-containing protein 4, NuMA-binding protein 1
Fondo	YEATS domain-containing protein 4 (YEATS4) is a ~26 kDa protein. Chromatin reader component of the NuA4 histone acetyltransferase (HAT) complex, a complex involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. Specifically recognizes and binds acylated histone H3, with a preference for histone H3 diacetylated at 'Lys-18' and 'Lys-27' (H3K18ac and H3K27ac) or histone H3 diacetylated at 'Lys-14' and 'Lys-27' (H3K14ac and H3K27ac). Also able to recognize and bind crotonylated histone H3. May also recognize and bind histone H3 succinylated at 'Lys-122' (H3K122succ); additional evidences are however required to confirm this result in vivo. Plays a key role in histone variant H2AZ1/H2A.Z deposition into specific chromatin regions: recognizes and binds H3K14ac and H3K27ac on the promoters of actively transcribed genes and recruits NuA4-related complex to deposit H2AZ1/H2A.Z. 1. Cai, Y. et al. (2003) The Journal of biological chemistry 278, 42733-6. PMID: 12963728 2. Doyon, Y. et al. (2004) Molecular and cellular biology 24, 1884-96. PMID: 14966270 3. Hsu, CC. et al. (2018) Genes & development 32, 58-69. PMID: 29437725 4. Hsu, CC. et al. (2018) Cell discovery 4, 28. PMID: 29900004 5. Cho, HJ. et al. (2018) ACS chemical biology 13, 2739-2746. PMID: 30071723 6. Wang, Y. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, 2365-2370. PMID: 29463709
Nota	For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Recombinant Human YEATS4 Protein, N-GST

Referencias

Datasheet

Human YEATS4 Recombinant Protein (N-GST).pdf

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Formula

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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