Human ZNF445 Recombinant Protein (N-His) (HD104012)

Name: Human ZNF445 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD104012
Price: 211 USD
Availability: InStock

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Número de catálogo	HD104012
Descripción	Recombinant Human ZNF445 Protein, N-His (HD104012) expressed in E. coli, spanning Leu478-Glu925. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P59923
Longitud de proteína	Leu478-Glu925
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	55.29 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	ZFP445, ZKSCAN15, ZNF168, ZNF445, Zinc finger protein 168, Zinc finger protein 445, Zinc finger protein with KRAB and SCAN domains 15
Fondo	Zinc finger protein 445 is a ~118 kDa protein. Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs). Acts together with ZFP57, but seems to be the major factor in human early embryonic imprinting maintenance. In contrast, in mice, ZFP57 plays the predominant role in imprinting maintenance. 1. Takahashi, N. et al. (2019) Genes & development 33, 49-54. PMID: 30602440
Nota	For research use only

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Datasheet

Human ZNF445 Recombinant Protein (N-His).pdf

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