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MeV Non-structural V Recombinant Protein (N-His) (VK815012)

MeV Non-structural V Recombinant Protein (N-His)
MeV Non-structural V Recombinant Protein (N-His)
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Especificación:
  • 50ug
  • 100ug
  • 1mg
Número:
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Vista general
Número de catálogoVK815012
Descripción
Recombinant MeV Non-structural protein V, N-His (VK815012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresiónE. coli
Número de accesoP0C774
Longitud de proteínaMet1-Gly231
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesMeasles virus (MeV)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosNon-structural protein V, P/V
Fondo

Non-structural protein V is a ~32 kDa protein. Plays an essential role in the inhibition of host immune response. Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway. Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state. Blocks the type I interferon signaling pathway by interacting with host TYK2 and thereby inhibiting downstream STAT1 and STAT2 phosphorylation. Blocks the type I interferon signaling pathway by disrupting the RIG-I signaling pathway.

1. Takeuchi, K. et al. (2003) FEBS letters 545, 177-82. PMID: 12804771
2. Parisien, JP. et al. (2009) Journal of virology 83, 7252-60. PMID: 19403670
3. Ramachandran, A. et al. (2008) Journal of virology 82, 8330-8. PMID: 18579593
4. Chinnakannan, SK. et al. (2013) PloS one 8, e57063. PMID: 23431397
5. Davis, ME. et al. (2014) Cell host & microbe 16, 19-30. PMID: 25011105
Nota For research use only
Imágenes
  • MeV Non-structural V Recombinant Protein (N-His)

    SDS-PAGE

    SDS-PAGE for Recombinant MeV V/Non-structural protein V Protein, N-His

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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