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Mouse ARTN/Artemin Recombinant Protein (C-Fc) (MP433021)

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概要
カタログ番号MP433021
説明
Recombinant Mouse ARTN/Artemin Protein, C-Fc (MP433021) expressed in Mammalian Cells, spanning Met1-Gly224. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
発現システムMammalian cells
アクセッション番号Q9Z0L2
タンパク質長Met1-Gly224
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Mus musculus (Mouse)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
予測分子量 50.13 kDa
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名ARTN, Artemin, EVN, Enovin, Neublastin
背景

Artemin is a ~23 kDa protein. Growth factor that supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Acts by binding to its coreceptor, GFRA3, leading to autophosphorylation and activation of the RET receptor. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue.

1. Bolon, B. et al. (2004) Toxicologic pathology 32, 275-94. PMID: 15204970
2. Veiga-Fernandes, H. et al. (2007) Nature 446, 547-51. PMID: 17322904
注意事項 For research use only
イメージ
参考文献
Formula
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Formula
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