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Anti-Mouse ARTN/Artemin Polyclonal Antibody (MP433014)

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Overview
Catalog No.MP433014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse ARTN/Artemin (Arg111-Gly224).
Target Artemin, Artn
Purification Purified by antigen affinity column.
Accession Q9Z0L2
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Artemin (ARTN) is a ~23 kDa protein. Growth factor that supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Acts by binding to its coreceptor, GFRA3, leading to autophosphorylation and activation of the RET receptor. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue.

1. Bolon, B. et al. (2004) Toxicologic pathology 32, 275-94. PMID: 15204970
2. Veiga-Fernandes, H. et al. (2007) Nature 446, 547-51. PMID: 17322904
Note For research use only.
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Formula
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