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Mouse CCL17/TARC Recombinant Protein (N-GST & C-His) (MV615022)

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Aperçu
Numéro de catalogueMV615022
Description
Recombinant Mouse CCL17/TARC Protein, N-GST & C-His (MV615022) expressed in E. coli, spanning Ala24-Pro93. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expressionE. coli
Numéro d'accèsQ9WUZ6
Longueur de protéineAla24-Pro93
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspècesMus musculus (Mouse)
Nature Recombinant
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >90% as determined by SDS-PAGE.
Masse moléculaire prédite 36.10 kDa
Forme Lyophilized
Tampon de stockage Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsC-C motif chemokine 17, CC chemokine TARC, CCL17, SCYA17, Small-inducible cytokine A17, TARC, Thymus and activation-regulated chemokine
Contexte

C-C motif chemokine 17 is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions.

1. Lieberam, I. et al. (1999) European journal of immunology 29, 2684-94. PMID: 10508243
2. Schaniel, C. et al. (1999) European journal of immunology 29, 2934-47. PMID: 10508268
3. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438
4. Fülle, L. et al. (2018) Glia 66, 2246-2261. PMID: 30277599
5. Kato, T. et al. (2011) Experimental dermatology 20, 669-74. PMID: 21521373
Note For research use only
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Formula
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Recommandation

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