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Mouse CCL17/TARC Recombinant Protein (N-GST & C-His) (MV615022)

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概要
カタログ番号MV615022
説明
Recombinant Mouse CCL17/TARC Protein, N-GST & C-His (MV615022) expressed in E. coli, spanning Ala24-Pro93. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
発現システムE. coli
アクセッション番号Q9WUZ6
タンパク質長Ala24-Pro93
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Mus musculus (Mouse)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
予測分子量 36.10 kDa
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名C-C motif chemokine 17, CC chemokine TARC, CCL17, SCYA17, Small-inducible cytokine A17, TARC, Thymus and activation-regulated chemokine
背景

C-C motif chemokine 17 is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions.

1. Lieberam, I. et al. (1999) European journal of immunology 29, 2684-94. PMID: 10508243
2. Schaniel, C. et al. (1999) European journal of immunology 29, 2934-47. PMID: 10508268
3. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438
4. Fülle, L. et al. (2018) Glia 66, 2246-2261. PMID: 30277599
5. Kato, T. et al. (2011) Experimental dermatology 20, 669-74. PMID: 21521373
注意事項 For research use only
イメージ
参考文献
Formula
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