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Mouse Endoglin/CD105 Recombinant Protein (C-His) (MB604011)

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概要
カタログ番号MB604011
説明
Recombinant Mouse CD105/ENG Protein, C-His (MB604011) expressed in Mammalian Cells, spanning Met1-Gly581. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
発現システムMammalian cells
アクセッション番号Q63961
タンパク質長Met1-Gly581
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Mus musculus (Mouse)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
予測分子量 63.65 kDa
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名CD105, END, ENG, Endoglin
背景

Endoglin is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.

1. Arthur, HM. et al. (2000) Developmental biology 217, 42-53. PMID: 10625534
2. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773
3. Sugden, WW. et al. (2017) Nature cell biology 19, 653-665. PMID: 28530658
4. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529
注意事項 For research use only
イメージ
参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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