Anti-Mouse CD105/ENG Polyclonal Antibody (MB604014)

Name: Anti-Mouse CD105/ENG Polyclonal Antibody
Brand: abinScience
SKU: MB604014
Price: 168 USD
Availability: InStock

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Spec:

50ug
100ug

Number:

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

MB604014

Species reactivity

Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse CD105/ENG (Asp37-Gly332).

Target

Endoglin (Cell surface MJ7/18 antigen) (CD antigen CD105)

Purification

Purified by antigen affinity column.

Accession

Q63961

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.

1. Arthur, HM. et al. (2000) Developmental biology 217, 42-53. PMID: 10625534

2. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773

3. Sugden, WW. et al. (2017) Nature cell biology 19, 653-665. PMID: 28530658

4. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Mouse CD105/ENG polyclonal antibody at 1ug/mL on recombinant Mouse CD105/ENG (Catalog No. MB604012).

References

Datasheet

Anti-Mouse CD105/ENG Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse CD105/ENG Polyclonal Antibody (MB604014)

Overview

Images

References

Datasheet

SDS

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