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Mouse ALCAM/CD166 Recombinant Protein (C-Fc) (MC678011)

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概要
カタログ番号MC678011
説明
Recombinant Mouse CD166/ALCAM Protein, C-Fc (MC678011) expressed in Mammalian Cells, spanning Trp28-Lys527. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
発現システムMammalian cells
アクセッション番号Q61490
タンパク質長Trp28-Lys527
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Mus musculus (Mouse)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
予測分子量 84.46 kDa
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名ALCAM, Activated leukocyte cell adhesion molecule, CD166, CD166 antigen, MEMD
背景

CD166 antigen is a ~65 kDa protein. Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction.

1. Chitteti, BR. et al. (2014) Blood 124, 519-29. PMID: 24740813
2. Iolyeva, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 978-90. PMID: 23169771
3. Hooker, RA. et al. (2015) Journal of musculoskeletal & neuronal interactions 15, 83-94. PMID: 25730656
4. Weiner, JA. et al. (2004) Molecular and cellular neurosciences 27, 59-69. PMID: 15345243
注意事項 For research use only
イメージ
参考文献
Formula
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