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Anti-Mouse ALCAM/CD166 Polyclonal Antibody (MC678014)

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Overview
Catalog No.MC678014
Description
Anti-Mouse CD166/ALCAM Polyclonal Antibody (MC678014) is a rabbit polyclonal antibody detecting Alcam. Suitable for Mouse and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityMouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse CD166/ALCAM (Thr30-Ile233).
Target Activated leukocyte cell adhesion molecule, Alcam, BEN, CD166, CD166 antigen, Protein DM-GRASP
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q61490
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

CD166 antigen (ALCAM) is a ~65 kDa protein. Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction.

1. Chitteti, BR. et al. (2014) Blood 124, 519-29. PMID: 24740813
2. Iolyeva, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 978-90. PMID: 23169771
3. Hooker, RA. et al. (2015) Journal of musculoskeletal & neuronal interactions 15, 83-94. PMID: 25730656
4. Weiner, JA. et al. (2004) Molecular and cellular neurosciences 27, 59-69. PMID: 15345243
Note For research use only
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Datasheet
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Formula
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Working Solution
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Anti-Mouse ALCAM/CD166 Polyclonal Antibody

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