Mouse TIM-1/KIM-1/HAVCR Recombinant Protein (C-His) (MV277012)

Name: Mouse TIM-1/KIM-1/HAVCR Recombinant Protein (C-His)
Brand: abinScience
SKU: MV277012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	MV277012
Description	Recombinant Mouse CD365/KIM-1/TIM-1/HAVCR1 Protein, C-His (MV277012) expressed in E. coli, spanning Tyr22-Gly237. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q5QNS5
Longueur de protéine	Tyr22-Gly237
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Mus musculus (Mouse)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	25.93 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	CD365, HAVCR1, HAVcr-1, Hepatitis A virus cellular receptor 1, KIM-1, KIM1, Kidney injury molecule 1, T-cell immunoglobulin and mucin domain-containing protein 1, T-cell immunoglobulin mucin receptor 1, T-cell membrane protein 1, TIM, TIM-1, TIM1, TIMD-1, TIMD1
Contexte	Hepatitis A virus cellular receptor 1 homolog is a ~33 kDa protein. Phosphatidylserine receptor that plays an important functional role in regulatory B-cell homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Also regulates expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as a regulator of T-cell proliferation. 1. Ding, Q. et al. (2011) The Journal of clinical investigation 121, 3645-56. PMID: 21821911 2. Yeung, MY. et al. (2015) American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 15, 942-53. PMID: 25645598 3. Xiao, S. et al. (2020) Cell reports 32, 107892. PMID: 32668241 4. Angiari, S. et al. (2014) Immunity 40, 542-53. PMID: 24703780 5. Xiao, S. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 1602-8. PMID: 25582854 6. Meyers, JH. et al. (2005) Nature immunology 6, 455-64. PMID: 15793576
Note	For research use only

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Mouse TIM-1/KIM-1/HAVCR Recombinant Protein (C-His).pdf

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