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Anti-Mouse CD365/KIM-1/TIM-1/HAVCR1 Polyclonal Antibody (MV277014)

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Overview
Catalog No.MV277014
Description
Anti-Mouse CD365/KIM-1/TIM-1/HAVCR1 Polyclonal Antibody (MV277014) is a rabbit polyclonal antibody detecting HAVCR1. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse CD365/KIM-1/TIM-1/HAVCR1 (Tyr22-Gly237).
Target CD365, HAVCR1, HAVcr-1, Hepatitis A virus cellular receptor 1, KIM-1, KIM1, Kidney injury molecule 1, T-cell immunoglobulin and mucin domain-containing protein 1, T-cell immunoglobulin mucin receptor 1, T-cell membrane protein 1, TIM, TIM-1, TIM1, TIMD-1, TIMD1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q5QNS5
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Hepatitis A virus cellular receptor 1 homolog (CD365/KIM-1) is a ~33 kDa protein. Phosphatidylserine receptor that plays an important functional role in regulatory B-cell homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Also regulates expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as a regulator of T-cell proliferation.

1. Ding, Q. et al. (2011) The Journal of clinical investigation 121, 3645-56. PMID: 21821911
2. Yeung, MY. et al. (2015) American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 15, 942-53. PMID: 25645598
3. Xiao, S. et al. (2020) Cell reports 32, 107892. PMID: 32668241
4. Angiari, S. et al. (2014) Immunity 40, 542-53. PMID: 24703780
5. Xiao, S. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 1602-8. PMID: 25582854
6. Meyers, JH. et al. (2005) Nature immunology 6, 455-64. PMID: 15793576
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Mouse CD365/KIM-1/TIM-1/HAVCR1 Polyclonal Antibody

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