Mouse TIM-3 Recombinant Protein (C-Strep) (MV029021)

Name: Mouse TIM-3 Recombinant Protein (C-Strep)
Brand: abinScience
SKU: MV029021
Price: 298 USD
Availability: InStock

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概要

カタログ番号	MV029021
説明	Recombinant Mouse CD366/HAVCR2/TIM-3 Protein, C-Strep (MV029021) expressed in Mammalian Cells, spanning Leu22-Arg191. Purity: >90% by SDS-PAGE. Highlights ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
発現システム	Mammalian cells
アクセッション番号	Q3KP82
タンパク質長	Leu22-Arg191
アプリケーション	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種	Mus musculus (Mouse)
性質	Recombinant
ターゲット	CD366, HAVCR2, HAVcr-2, Hepatitis A virus cellular receptor 2, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIM-3, TIM3, TIMD-3, TIMD3
エンドトキシンレベル	Please contact with the lab for this information.
純度	>90% as determined by SDS-PAGE.
予測分子量	22.00 kDa
形態	Lyophilized
保存バッファー	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
再構成	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	CD366, HAVCR2, HAVcr-2, Hepatitis A virus cellular receptor 2, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIM-3, TIM3, TIMD-3, TIMD3
背景	Hepatitis A virus cellular receptor 2 homolog is a ~30 kDa protein. Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. 1. Anderson, AC. et al. (2007) Science (New York, N.Y.) 318, 1141-3. PMID: 18006747 2. Monney, L. et al. (2002) Nature 415, 536-41. PMID: 11823861 3. Sabatos, CA. et al. (2003) Nature immunology 4, 1102-10. PMID: 14556006 4. Lee, J. et al. (2011) Molecular and cellular biology 31, 3963-74. PMID: 21807895 5. Rangachari, M. et al. (2012) Nature medicine 18, 1394-400. PMID: 22863785 6. Jayaraman, P. et al. (2010) The Journal of experimental medicine 207, 2343-54. PMID: 20937702 7. Gorman, JV. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 3133-42. PMID: 24567532 8. DeKruyff, RH. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 184, 1918-30. PMID: 20083673 9. Nakayama, M. et al. (2009) Blood 113, 3821-30. PMID: 19224762
注意事項	For research use only

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参考文献

データシート

Mouse TIM-3 Recombinant Protein (C-Strep).pdf

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Mouse TIM-3 Recombinant Protein (C-Strep) (MV029021)

概要

イメージ

参考文献

データシート

SDS

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