

| Numéro de catalogue | MV492012 |
|---|---|
| Description |
Recombinant Mouse IL19 Protein, N-His (MV492012) expressed in E. coli, spanning Leu25-Ala176. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q8CJ70 |
| Longueur de protéine | Leu25-Ala176 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Mus musculus (Mouse) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 19.90 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | IL-19, IL19, Interleukin-19, Melanoma differentiation-associated protein-like protein, NG.1, ZMDA1 |
| Contexte | Interleukin-19 is a ~20 kDa protein. Cytokine that functions as an anti-inflammatory and proangiogenic factor. Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL5. Produced by osteocytes, stimulates granulopoiesis and neutrophil formation. Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3. 1. Liao, YC. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 169, 4288-97. PMID: 12370360 2. Kako, F. et al. (2016) American journal of physiology. Cell physiology 310, C931-41. PMID: 27053520 3. Liao, SC. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 6712-8. PMID: 15557163 4. Xiao, M. et al. (2021) Blood 137, 3533-3547. PMID: 33684929 |
| Note | For research use only |
Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.
Courrier : [email protected]
+86-027-65523339
Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine
中文
English
한국어
日本語
Español
Français
Русский