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Anti-Mouse IL19 Polyclonal Antibody (MV492014)

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Overview
Catalog No.MV492014
Description
Anti-Mouse IL19 Polyclonal Antibody (MV492014) is a rabbit polyclonal antibody detecting IL19. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse IL19 (Leu25-Ala176).
Target IL-19, IL19, Interleukin-19, Melanoma differentiation-associated protein-like protein, NG.1, ZMDA1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q8CJ70
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Interleukin-19 (IL19) is a ~20 kDa protein. Cytokine that functions as an anti-inflammatory and proangiogenic factor. Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL5. Produced by osteocytes, stimulates granulopoiesis and neutrophil formation. Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3.

1. Liao, YC. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 169, 4288-97. PMID: 12370360
2. Kako, F. et al. (2016) American journal of physiology. Cell physiology 310, C931-41. PMID: 27053520
3. Liao, SC. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 6712-8. PMID: 15557163
4. Xiao, M. et al. (2021) Blood 137, 3533-3547. PMID: 33684929
Note For research use only
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Formula
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Formula
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Anti-Mouse IL19 Polyclonal Antibody

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