Mouse IL19 Recombinant Protein (N-His) (MV492012)

Name: Mouse IL19 Recombinant Protein (N-His)
Brand: abinScience
SKU: MV492012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MV492012
Description	Recombinant Mouse IL19 Protein, N-His (MV492012) expressed in E. coli, spanning Leu25-Ala176. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q8CJ70
Protein length	Leu25-Ala176
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	19.90 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	IL-19, IL19, Interleukin-19, Melanoma differentiation-associated protein-like protein, NG.1, ZMDA1
Background	Interleukin-19 is a ~20 kDa protein. Cytokine that functions as an anti-inflammatory and proangiogenic factor. Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL5. Produced by osteocytes, stimulates granulopoiesis and neutrophil formation. Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3. 1. Liao, YC. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 169, 4288-97. PMID: 12370360 2. Kako, F. et al. (2016) American journal of physiology. Cell physiology 310, C931-41. PMID: 27053520 3. Liao, SC. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 6712-8. PMID: 15557163 4. Xiao, M. et al. (2021) Blood 137, 3533-3547. PMID: 33684929
Note	For research use only

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Mouse IL19 Recombinant Protein (N-His).pdf

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Mouse IL19 Recombinant Protein (N-His) (MV492012)

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