

| カタログ番号 | MV492012 |
|---|---|
| 説明 |
Recombinant Mouse IL19 Protein, N-His (MV492012) expressed in E. coli, spanning Leu25-Ala176. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q8CJ70 |
| タンパク質長 | Leu25-Ala176 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Mus musculus (Mouse) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 19.90 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | IL-19, IL19, Interleukin-19, Melanoma differentiation-associated protein-like protein, NG.1, ZMDA1 |
| 背景 | Interleukin-19 is a ~20 kDa protein. Cytokine that functions as an anti-inflammatory and proangiogenic factor. Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL5. Produced by osteocytes, stimulates granulopoiesis and neutrophil formation. Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3. 1. Liao, YC. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 169, 4288-97. PMID: 12370360 2. Kako, F. et al. (2016) American journal of physiology. Cell physiology 310, C931-41. PMID: 27053520 3. Liao, SC. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 6712-8. PMID: 15557163 4. Xiao, M. et al. (2021) Blood 137, 3533-3547. PMID: 33684929 |
| 注意事項 | For research use only |
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