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Mouse IL-1Rrp2/IL-1R6 Recombinant Protein (C-Fc) (MV045021)

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概要
カタログ番号MV045021
説明
Recombinant Mouse IL1RL2/IL-36R Protein, C-Fc (MV045021) expressed in Mammalian Cells, spanning Asp22-Arg338. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
発現システムMammalian cells
アクセッション番号Q9ERS7
タンパク質長Asp22-Arg338
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Mus musculus (Mouse)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
予測分子量 64.35 kDa
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名EC:3.2.2.6, IL-1Rrp2, IL-36 receptor, IL-36R, IL1R-rp2, IL1RL2, IL1RRP2, Interleukin-1 receptor-like 2, Interleukin-1 receptor-related protein 2
背景

Interleukin-1 receptor-like 2 is a ~65 kDa protein. Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.

注意事項 For research use only
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参考文献
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