Anti-Mouse IL1RL2/IL-36R Polyclonal Antibody (MV045014)

Name: Anti-Mouse IL1RL2/IL-36R Polyclonal Antibody
Brand: abinScience
SKU: MV045014
Price: 96 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

MV045014

Description

Anti-Mouse IL1RL2/IL-36R Polyclonal Antibody (MV045014) is a rabbit polyclonal antibody detecting IL-36R in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse IL1RL2/IL-36R (Met29-Ile331).

Target

IL1R-rp2, IL1RL2, IL1RRP2, IL-1Rrp2, IL-36 receptor, Interleukin-1 receptor-related protein 2, Interleukin-1 receptor-like 2, IL-36R

Purification

Purified by antigen affinity column.

Accession

Q9ERS7

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Interleukin-1 receptor-like 2 (IL1RL2/IL-36R) is a ~65 kDa protein. Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-IL1RL2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate
Lane 2: HL-60 cell lysate

References

Datasheet

Anti-Mouse IL1RL2/IL-36R Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse IL1RL2/IL-36R Polyclonal Antibody (MV045014)

Overview

Images

References

Datasheet

SDS

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