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Обзор
Каталожный номерMY457022
Описание
Recombinant Mouse IL4 Protein, N-GST & C-His (MY457022) expressed in E. coli, spanning His23-Ser140. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессииE. coli
Номер доступаP07750
Длина белкаHis23-Ser140
ПримененияELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
ВидыMus musculus (Mouse)
Характер Recombinant
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса 41.49 kDa
Форма Lyophilized
Буфер хранения Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Реконституция Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияB-cell stimulatory factor 1, BSF-1, Binetrakin, IL-4, IL4, Interleukin-4, Lymphocyte stimulatory factor 1, Pitrakinra
Фон

Interleukin-4 is a ~15 kDa protein. Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. Induces the expression of class II MHC molecules on resting B-cells. Enhances both secretion and cell surface expression of IgE and IgG1. Also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.

1. Lee, F. et al. (1986) Proceedings of the National Academy of Sciences of the United States of America 83, 2061-5. PMID: 3083412
2. Sideras, P. et al. (1987) Advances in experimental medicine and biology 213, 227-36. PMID: 3498301
3. Terawaki, S. et al. (2015) The Journal of cell biology 210, 1133-52. PMID: 26416964
4. Moon, ML. et al. (2015) Behavior genetics 45, 451-60. PMID: 25772794
5. Bogale, TMH. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2681-2688. PMID: 28202615
6. Edukulla, R. et al. (2015) The Journal of biological chemistry 290, 13510-20. PMID: 25847241
7. Kaplan, MH. et al. (1996) Immunity 4, 313-9. PMID: 8624821
Примечание For research use only
Изображения
Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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