Anti-Mouse IL-4 Polyclonal Antibody (MY457014)

Name: Anti-Mouse IL-4 Polyclonal Antibody
Brand: abinScience
SKU: MY457014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

MY457014

Description

Anti-Mouse IL4 Polyclonal Antibody (MY457014) is a rabbit polyclonal antibody detecting IL4. Suitable for Mouse.

Species reactivity

Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse IL4 (His23-Ser140).

Target

B-cell stimulatory factor 1, BSF-1, Binetrakin, IL-4, IL4, Interleukin-4, Lymphocyte stimulatory factor 1, Pitrakinra

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P07750

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Interleukin-4 (IL4) is a ~15 kDa protein. Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. Induces the expression of class II MHC molecules on resting B-cells. Enhances both secretion and cell surface expression of IgE and IgG1. Also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.

1. Lee, F. et al. (1986) Proceedings of the National Academy of Sciences of the United States of America 83, 2061-5. PMID: 3083412

2. Sideras, P. et al. (1987) Advances in experimental medicine and biology 213, 227-36. PMID: 3498301

3. Terawaki, S. et al. (2015) The Journal of cell biology 210, 1133-52. PMID: 26416964

4. Moon, ML. et al. (2015) Behavior genetics 45, 451-60. PMID: 25772794

5. Bogale, TMH. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2681-2688. PMID: 28202615

6. Edukulla, R. et al. (2015) The Journal of biological chemistry 290, 13510-20. PMID: 25847241

7. Kaplan, MH. et al. (1996) Immunity 4, 313-9. PMID: 8624821

Note

For research use only

Images

References

Datasheet

Anti-Mouse IL-4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse IL-4 Polyclonal Antibody (MY457014)

Overview

Images

References

Datasheet

SDS

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