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| カタログ番号 | MW709012 |
|---|---|
| 説明 |
Recombinant Mouse NUMB Protein, N-His (MW709012) expressed in E. coli, spanning Val16-Ala200. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q9QZS3 |
| タンパク質長 | Val16-Ala200 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Mus musculus (Mouse) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 23.25 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | C14orf41, NUMB, Protein S171, Protein numb homolog, h-Numb |
| 背景 | Protein numb homolog is a ~70 kDa protein. Regulates clathrin-mediated receptor endocytosis. Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. 1. Zhong, W. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 6844-9. PMID: 10841580 2. Petersen, PH. et al. (2002) Nature 419, 929-34. PMID: 12410312 3. Petersen, PH. et al. (2004) Nature neuroscience 7, 803-11. PMID: 15273690 4. Kuo, CT. et al. (2006) Cell 127, 1253-64. PMID: 17174898 |
| 注意事項 | For research use only |
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