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Anti-Mouse NUMB Polyclonal Antibody (MW709014)

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Overview
Catalog No.MW709014
Description
Anti-Mouse NUMB Polyclonal Antibody (MW709014) is a rabbit polyclonal antibody detecting h-Numb. Suitable for Rat, Mouse, and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Mouse NUMB (Val16-Ala200).
Target C14orf41, NUMB, Protein S171, Protein numb homolog, h-Numb
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9QZS3
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Protein numb homolog is a ~70 kDa protein. Regulates clathrin-mediated receptor endocytosis. Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity.

1. Zhong, W. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 6844-9. PMID: 10841580
2. Petersen, PH. et al. (2002) Nature 419, 929-34. PMID: 12410312
3. Petersen, PH. et al. (2004) Nature neuroscience 7, 803-11. PMID: 15273690
4. Kuo, CT. et al. (2006) Cell 127, 1253-64. PMID: 17174898
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Mouse NUMB Polyclonal Antibody

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