

| カタログ番号 | MP096021 |
|---|---|
| 説明 |
Recombinant Mouse RTN4R/NgR1/Nogor Protein, C-Fc (MP096021) expressed in Mammalian Cells, spanning Cys27-Ser447. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | Mammalian cells |
| アクセッション番号 | Q99PI8 |
| タンパク質長 | Cys27-Ser447 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Mus musculus (Mouse) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 73.90 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | NOGOR, NgR, Nogo receptor, Nogo-66 receptor, RTN4R, Reticulon-4 receptor |
| 背景 | Reticulon-4 receptor is a ~50 kDa protein. Receptor for RTN4, OMG and MAG. Functions as a receptor for the sialylated gangliosides GT1b and GM1. Besides, functions as a receptor for chondroitin sulfate proteoglycans. Can also bind heparin. Intracellular signaling cascades are triggered via the coreceptor NGFR. 1. Fournier, AE. et al. (2001) Nature 409, 341-6. PMID: 11201742 2. Liu, BP. et al. (2002) Science (New York, N.Y.) 297, 1190-3. PMID: 12089450 3. Kim, JE. et al. (2004) Neuron 44, 439-51. PMID: 15504325 4. Williams, G. et al. (2008) The Journal of biological chemistry 283, 16641-52. PMID: 18411262 5. Nakaya, N. et al. (2012) The Journal of biological chemistry 287, 37171-84. PMID: 22923615 6. Dickendesher, TL. et al. (2012) Nature neuroscience 15, 703-12. PMID: 22406547 7. Wills, ZP. et al. (2012) Neuron 73, 466-81. PMID: 22325200 9. Palandri, A. et al. (2015) Cell death & disease 6, e1876. PMID: 26335717 |
| 注意事項 | For research use only |
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