Anti-Mouse RTN4R Polyclonal Antibody (MP096014)

Name: Anti-Mouse RTN4R Polyclonal Antibody
Brand: abinScience
SKU: MP096014
Price: 168 USD
Availability: InStock

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Overview

Catalog No.

MP096014

Species reactivity

Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse RTN4R (Thr25-Gly308).

Target

Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor) (Nogo66 receptor-1) (NgR1)

Purification

Purified by antigen affinity column.

Accession

Q99PI8

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Reticulon-4 receptor (RTN4R/NgR1) is a ~50 kDa protein. Receptor for RTN4, OMG and MAG. Functions as a receptor for the sialylated gangliosides GT1b and GM1. Besides, functions as a receptor for chondroitin sulfate proteoglycans. Can also bind heparin. Intracellular signaling cascades are triggered via the coreceptor NGFR.

1. Fournier, AE. et al. (2001) Nature 409, 341-6. PMID: 11201742

2. Liu, BP. et al. (2002) Science (New York, N.Y.) 297, 1190-3. PMID: 12089450

3. Kim, JE. et al. (2004) Neuron 44, 439-51. PMID: 15504325

4. Williams, G. et al. (2008) The Journal of biological chemistry 283, 16641-52. PMID: 18411262

5. Nakaya, N. et al. (2012) The Journal of biological chemistry 287, 37171-84. PMID: 22923615

6. Dickendesher, TL. et al. (2012) Nature neuroscience 15, 703-12. PMID: 22406547

7. Wills, ZP. et al. (2012) Neuron 73, 466-81. PMID: 22325200

9. Palandri, A. et al. (2015) Cell death & disease 6, e1876. PMID: 26335717

Note

For research use only.

Images

References

Datasheet

Anti-Mouse RTN4R Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Assay Kits

Anti-Mouse RTN4R Polyclonal Antibody (MP096014)

Overview

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References

Datasheet

SDS

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