Mouse RTN4R/NgR1/Nogor Recombinant Protein (C-Fc) (MP096021)

Name: Mouse RTN4R/NgR1/Nogor Recombinant Protein (C-Fc)
Brand: abinScience
SKU: MP096021
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	MP096021
Description	Recombinant Mouse RTN4R/NgR1/Nogor Protein, C-Fc (MP096021) expressed in Mammalian Cells, spanning Cys27-Ser447. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q99PI8
Protein length	Cys27-Ser447
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	73.90 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	NOGOR, NgR, Nogo receptor, Nogo-66 receptor, RTN4R, Reticulon-4 receptor
Background	Reticulon-4 receptor is a ~50 kDa protein. Receptor for RTN4, OMG and MAG. Functions as a receptor for the sialylated gangliosides GT1b and GM1. Besides, functions as a receptor for chondroitin sulfate proteoglycans. Can also bind heparin. Intracellular signaling cascades are triggered via the coreceptor NGFR. 1. Fournier, AE. et al. (2001) Nature 409, 341-6. PMID: 11201742 2. Liu, BP. et al. (2002) Science (New York, N.Y.) 297, 1190-3. PMID: 12089450 3. Kim, JE. et al. (2004) Neuron 44, 439-51. PMID: 15504325 4. Williams, G. et al. (2008) The Journal of biological chemistry 283, 16641-52. PMID: 18411262 5. Nakaya, N. et al. (2012) The Journal of biological chemistry 287, 37171-84. PMID: 22923615 6. Dickendesher, TL. et al. (2012) Nature neuroscience 15, 703-12. PMID: 22406547 7. Wills, ZP. et al. (2012) Neuron 73, 466-81. PMID: 22325200 9. Palandri, A. et al. (2015) Cell death & disease 6, e1876. PMID: 26335717
Note	For research use only

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Datasheet

Mouse RTN4R/NgR1/Nogor Recombinant Protein (C-Fc).pdf

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Mouse RTN4R/NgR1/Nogor Recombinant Protein (C-Fc) (MP096021)

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