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| カタログ番号 | MA988012 |
|---|---|
| 説明 |
Recombinant Mouse SEMA4A Protein, N-His (MA988012) expressed in E. coli, spanning Arg41-Cys546. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q62178 |
| タンパク質長 | Arg41-Cys546 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Mus musculus (Mouse) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 58.47 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | SEMA4A, SEMAB, SEMB, Sema B, Semaphorin-4A, Semaphorin-B |
| 背景 | Semaphorin-4A is a ~83 kDa protein. Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. Regulates glutamatergic and GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner and promotes the development of excitatory synapses in a PLXNB2-dependent manner. Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. Promotes phosphorylation of TIMD2. 1. Toyofuku, T. et al. (2007) The EMBO journal 26, 1373-84. PMID: 17318185 2. Yukawa, K. et al. (2010) International journal of molecular medicine 25, 225-30. PMID: 20043131 3. McDermott, JE. et al. (2018) Molecular and cellular neurosciences 92, 50-66. PMID: 29981480 4. Kumanogoh, A. et al. (2005) Immunity 22, 305-16. PMID: 15780988 5. Kumanogoh, A. et al. (2002) Nature 419, 629-33. PMID: 12374982 |
| 注意事項 | For research use only |
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