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Mouse VISTA/B7-H5/PD-1H Recombinant Protein (C-Fc) (MP543021)

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Vista general
Número de catálogoMP543021
Descripción
Recombinant Mouse VSIR/VISTA Protein, C-Fc (MP543021) expressed in Mammalian Cells, spanning Phe33-Ala191. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresiónMammalian cells
Número de accesoQ9D659
Longitud de proteínaPhe33-Ala191
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesMus musculus (Mouse)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Peso molecular predicho 46.10 kDa
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosC10orf54, Platelet receptor Gi24, SISP1, Sisp-1, Stress-induced secreted protein-1, V-set domain-containing immunoregulatory receptor, V-set immunoregulatory receptor, V-type immunoglobulin domain-containing suppressor of T-cell activation, VISTA, VSIR
Fondo

V-type immunoglobulin domain-containing suppressor of T-cell activation is a ~33 kDa protein. Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14-mediated MMP2 activation.

1. Wang, L. et al. (2011) The Journal of experimental medicine 208, 577-92. PMID: 21383057
2. Flies, DB. et al. (2014) The Journal of clinical investigation 124, 1966-75. PMID: 24743150
3. Wang, L. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 14846-51. PMID: 25267631
4. Aloia, L. et al. (2010) The Journal of biological chemistry 285, 7776-83. PMID: 20042595
Nota For research use only
Imágenes
Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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