Anti-Human MSLN/Mesothelin Reference Antibody (Amatuximab, RUO) (HC496026)

Name: Anti-Human MSLN/Mesothelin Reference Antibody (Amatuximab, RUO)
Brand: abinScience
SKU: HC496026
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HC496026
Description	Amatuximab (HC496026) is a research-grade recombinant antibody targeting CAK1 antigen. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôte	Chimeric
Clonalité	Monoclonal
Isotype	IgG1-kappa
Applications testées	FCM
Cible	CAK1 antigen, MPF, MSLN, Megakaryocyte-potentiating factor, Mesothelin, Mesothelin, cleaved form, Pre-pro-megakaryocyte-potentiating factor
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q13421
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	MORAb-009, 931402-35-6
Contexte	Mesothelin (MSLN) is a ~68 kDa protein. Membrane-anchored forms may play a role in cellular adhesion.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SEC-HPLC

SEC-HPLC detection for Research Grade Amatuximab.
Bioactivity

Detects MSLN in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Amatuximab.
Flow CytoMetry

Flow-cytometry using anti-human MSLN antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human MSLN monoclonal antibody (Catalog: HC496026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.