Anti-Human MSLN/Mesothelin Reference Antibody (Amatuximab, RUO) (HC496026)

Name: Anti-Human MSLN/Mesothelin Reference Antibody (Amatuximab, RUO)
Brand: abinScience
SKU: HC496026
Price: 176 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HC496026
説明	Amatuximab (HC496026) is a research-grade recombinant antibody targeting CAK1 antigen. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
宿主種	Chimeric
クローン性	Monoclonal
アイソタイプ	IgG1-kappa
テスト済みアプリケーション	FCM
ターゲット	CAK1 antigen, MPF, MSLN, Megakaryocyte-potentiating factor, Mesothelin, Mesothelin, cleaved form, Pre-pro-megakaryocyte-potentiating factor
エンドトキシンレベル	< 10 EU/mg
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q13421
形態	Liquid
保存バッファー	0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	MORAb-009, 931402-35-6
背景	Mesothelin (MSLN) is a ~68 kDa protein. Membrane-anchored forms may play a role in cellular adhesion.
注意事項	For research use only. Not suitable for clinical or therapeutic use.

イメージ

SEC-HPLC

SEC-HPLC detection for Research Grade Amatuximab.
Bioactivity

Detects MSLN in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Amatuximab.
Flow CytoMetry

Flow-cytometry using anti-human MSLN antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human MSLN monoclonal antibody (Catalog: HC496026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.