Anti-Canine CTLA-4 Reference Antibody (12B3, RUO) (CB651016)

Name: Anti-Canine CTLA-4 Reference Antibody (12B3, RUO)
Brand: abinScience
SKU: CB651016
Price: 370 USD
Availability: InStock

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100ug
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Обзор

Каталожный номер	CB651016
Описание	Anti-Dog CD152/CTLA4 Antibody (12B3) (CB651016) is a research-grade recombinant antibody targeting CD152. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Canine
Применения	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Хозяинский вид	Canine
Клоональность	Monoclonal
Изотип	IgG2, kappa
ID клона	12B3
Цель	CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q9XSI1
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

SDS-PAGE

SDS-PAGE for Research Grade Anti-Dog CD152/CTLA4 Antibody (12B3)

Ссылки

Даташит

Anti-Canine CTLA-4 Reference Antibody (12B3, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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