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Anti-Canine CTLA-4 Reference Antibody (39A11, RUO) (CB651026)

Anti-Canine CTLA-4 Reference Antibody (39A11, RUO)
Anti-Canine CTLA-4 Reference Antibody (39A11, RUO)
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Aperçu
Numéro de catalogueCB651026
Description
Anti-Dog CD152/CTLA4 Antibody (39A11) (CB651026) is a research-grade recombinant antibody targeting CD152. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesCanine
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôteCanine
ClonalitéMonoclonal
IsotypeIgG2, kappa
ID de clone39A11
Cible CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Niveau d'endotoxines < 10 EU/mg
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q9XSI1
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Canine CTLA-4 Reference Antibody (39A11, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Dog CD152/CTLA4 Antibody (39A11)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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