Anti-Canine CTLA-4 Reference Antibody (12B3, RUO) (CB651016)

Name: Anti-Canine CTLA-4 Reference Antibody (12B3, RUO)
Brand: abinScience
SKU: CB651016
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	CB651016
Description	Anti-Dog CD152/CTLA4 Antibody (12B3) (CB651016) is a research-grade recombinant antibody targeting CD152. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Canine
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host species	Canine
Clonality	Monoclonal
Isotype	IgG2, kappa
Clone ID	12B3
Target	HA, Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9XSI1
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Dog CD152/CTLA4 Antibody (12B3)

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Datasheet

Anti-Canine CTLA-4 Reference Antibody (12B3, RUO).pdf

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Anti-Canine CTLA-4 Reference Antibody (12B3, RUO) (CB651016)

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