Anti-Influenza A virus HA/Hemagglutinin Broadly Neutralizing Reference Antibody (CR8020, RUO) (VK515096)

Name: Anti-Influenza A virus HA/Hemagglutinin Broadly Neutralizing Reference Antibody (CR8020, RUO)
Brand: abinScience
SKU: VK515096
Price: 370 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

VK515096

説明

Anti-Flu A (H3N2) HA/Hemagglutinin Broadly Neutralizing Antibody (CR8020) (VK515096) is a research-grade recombinant antibody targeting Hemagglutinin. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

種反応性

Influenza A virus (H3, H4, H7, H10, H14, H15 subtype)

アプリケーション

ELISA, Bioactivity: FCM, Functional assay, Research in vivo

宿主種

Human

クローン性

Monoclonal

アイソタイプ

IgG1-lambda

クローンID

CR8020

発現システム

Mammalian cells

性質

Recombinant

ターゲット

HA, Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain

エンドトキシンレベル

< 10 EU/mg as determined by LAL method.

純度

>95% as determined by SDS-PAGE.

精製

Protein A/G purified from cell culture supernatant.

形態

Liquid

保存バッファー

0.01M PBS pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:2000-1:20000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Hemagglutinin (HA) is a ~63 kDa protein. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.

注意事項

For research use only. Not suitable for clinical or therapeutic use.

イメージ

SDS-PAGE

SDS-PAGE for Research Grade Anti-Flu A (H3N2) HA/Hemagglutinin Broadly Neutralizing Antibody (CR8020)

参考文献

データシート

Anti-Influenza A virus HA/Hemagglutinin Broadly Neutralizing Reference Antibody (CR8020, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Influenza A virus HA/Hemagglutinin Broadly Neutralizing Reference Antibody (CR8020, RUO) (VK515096)

概要

イメージ

参考文献

データシート

SDS