Anti-HCV Envelope glycoprotein E2 Reference Antibody (MBL-HCV1, RUO) (VK681016)

Name: Anti-HCV Envelope glycoprotein E2 Reference Antibody (MBL-HCV1, RUO)
Brand: abinScience
SKU: VK681016
Price: 370 USD
Availability: InStock

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100ug
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Vista general

Número de catálogo	VK681016
Descripción	Anti-HCV NS1/Envelope glycoprotein E2 (MBL-HCV1) (VK681016) is a research-grade recombinant antibody targeting NS1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Hepatitis C Virus (HCV)
Aplicaciones	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1-kappa
ID de clon	MBL-HCV1
Aplicaciones probadas	WB
Objetivo	Envelope glycoprotein E2, NS1, gp68, gp70
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P27958
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	MBL-HCV1, MBLHCV1
Fondo	Genome polyprotein (NS1/gp68) is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable). 1. Ivanyi-Nagy, R. et al. (2008) Nucleic acids research 36, 712-25. PMID: 18033802 2. Anjum, S. et al. (2013) Molecular medicine reports 8, 487-92. PMID: 23799612 3. Kittlesen, DJ. et al. (2000) The Journal of clinical investigation 106, 1239-49. PMID: 11086025 4. Waggoner, SN. et al. (2007) Journal of leukocyte biology 82, 1407-19. PMID: 17881511 5. Ruggieri, A. et al. (2003) Virus research 97, 103-10. PMID: 14602201
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

Western blot

Western blot analysis was performed using anti-glycoprotein E2 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant hepatitis C virus (Catalog No: VK681011)
Lane 2: negative control
Bioactivity

Detects recombinant HCV NS1/gp68/gp70/Envelope glycoprotein E2 (Catalog No: VK681011) in indirect ELISA