Anti-Human aPC/Activated protein C Reference Antibody (TPP-2312/BAY1316786, RUO) (HY476016)

Name: Anti-Human aPC/Activated protein C Reference Antibody (TPP-2312/BAY1316786, RUO)
Brand: abinScience
SKU: HY476016
Price: 326 USD
Availability: InStock

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Número de catálogo	HY476016
Descripción	Anti-Human APC/Activated protein C (TPP-2312/BAY1316786) (HY476016) is a research-grade recombinant antibody targeting Anticoagulant protein C. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG2
ID de clon	TPP-2312/BAY1316786
Objetivo	Anticoagulant protein C, Vitamin K-dependent protein C, Blood coagulation factor XIV, Autoprothrombin IIA
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P04070
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	TPP-2312, BAY1316786
Fondo	Vitamin K-dependent protein C (APC/Activated protein C) is a ~52 kDa protein. Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. 1. Kovács, KB. et al. (2015) Thrombosis research 135, 718-26. PMID: 25618265 2. Cao, Q. et al. (2025) Nature 639, 816-824. PMID: 39880037 3. Ding, Q. et al. (2015) Blood 125, 2428-34. PMID: 25651845
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)