Anti-Human PC/aPC Antibody (R41C17) (HY476013)

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50ug
100ug
1mg

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Datasheet

Overview

Catalog No.

HY476013

Description

Anti-Human PC/aPC Antibody (R41C17) [R41C17] (HY476013) is a mouse monoclonal antibody detecting aPC in ELISA. Suitable for Human.

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a

Clone ID

R41C17

Clonality

Monoclonal

Target

Anticoagulant protein C, Vitamin K-dependent protein C, Blood coagulation factor XIV, Autoprothrombin IIA, PROC, aPC, Activated protein C

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P04070

RRID

Anti-Human PC/aPC Antibody (R41C17) (abinScience Cat# HY476013, RRID:AB_3729648)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Vitamin K-dependent protein C (PC/aPC) is a ~52 kDa protein. Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function.

1. Kovács, KB. et al. (2015) Thrombosis research 135, 718-26. PMID: 25618265

2. Cao, Q. et al. (2025) Nature 639, 816-824. PMID: 39880037

3. Ding, Q. et al. (2015) Blood 125, 2428-34. PMID: 25651845

Note

For research use only.

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