Anti-Human aPC/Activated protein C Reference Antibody (TPP-2312/BAY1316786, RUO) (HY476016)

Name: Anti-Human aPC/Activated protein C Reference Antibody (TPP-2312/BAY1316786, RUO)
Brand: abinScience
SKU: HY476016
Price: 326 USD
Availability: InStock

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Overview

Catalog No.	HY476016
Description	Anti-Human APC/Activated protein C (TPP-2312/BAY1316786) (HY476016) is a research-grade recombinant antibody targeting Anticoagulant protein C. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG2
Clone ID	TPP-2312/BAY1316786
Clonality	Monoclonal
Target	Anticoagulant protein C, Vitamin K-dependent protein C, Blood coagulation factor XIV, Autoprothrombin IIA
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P04070
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	TPP-2312, BAY1316786
Background	Vitamin K-dependent protein C (APC/Activated protein C) is a ~52 kDa protein. Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. 1. Kovács, KB. et al. (2015) Thrombosis research 135, 718-26. PMID: 25618265 2. Cao, Q. et al. (2025) Nature 639, 816-824. PMID: 39880037 3. Ding, Q. et al. (2015) Blood 125, 2428-34. PMID: 25651845
Note	For research use only. Not suitable for clinical or therapeutic use.