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Anti-Human CCL5/RANTES Reference Antibody (VLST-002, RUO) (HY346026)

Anti-Human CCL5/RANTES Reference Antibody (VLST-002, RUO)
Anti-Human CCL5/RANTES Reference Antibody (VLST-002, RUO)
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Aperçu
Numéro de catalogueHY346026
Description
Anti-Human CCL5/RANTES Antibody (VLST-002) (HY346026) is a research-grade recombinant antibody targeting TCP228. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
IsotypeIgG1-kappa
ID de cloneVLST-002
Système d'expression Mammalian cells
Cible TCP228, C-C motif chemokine 5, CCL5, T cell-specific protein P228, D17S136E, Small-inducible cytokine A5, SIS-delta, SCYA5, T-cell-specific protein RANTES, Eosinophil chemotactic cytokine, EoCP
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P13501
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsVLST-002, VLST002, VLST002
Contexte

C-C motif chemokine 5 (CCL5/RANTES) is a ~9 kDa protein. Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

1. Kameyoshi, Y. et al. (1992) The Journal of experimental medicine 176, 587-92. PMID: 1380064
2. Lim, JK. et al. (2005) Journal of leukocyte biology 78, 442-52. PMID: 15923218
3. Capoulade-Métay, C. et al. (2006) Immunogenetics 58, 533-41. PMID: 16791620
4. Cocchi, F. et al. (1995) Science (New York, N.Y.) 270, 1811-5. PMID: 8525373
5. Proost, P. et al. (1998) The Journal of biological chemistry 273, 7222-7. PMID: 9516414
6. Liu, B. et al. (2013) Diabetologia 56, 2467-76. PMID: 23979485
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10) (HV080407)
Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Images
  • Anti-Human CCL5/RANTES Reference Antibody (VLST-002, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CCL5/RANTES Antibody (VLST-002)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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