Anti-Human CCL5/RANTES Reference Antibody (VLST-002, RUO) (HY346026)

Name: Anti-Human CCL5/RANTES Reference Antibody (VLST-002, RUO)
Brand: abinScience
SKU: HY346026
Price: 370 USD
Availability: InStock

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概要

カタログ番号	HY346026
説明	Anti-Human CCL5/RANTES Antibody (VLST-002) (HY346026) is a research-grade recombinant antibody targeting TCP228. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
アイソタイプ	IgG1-kappa
クローンID	VLST-002
発現システム	Mammalian cells
ターゲット	TCP228, C-C motif chemokine 5, CCL5, T cell-specific protein P228, D17S136E, Small-inducible cytokine A5, SIS-delta, SCYA5, T-cell-specific protein RANTES, Eosinophil chemotactic cytokine, EoCP
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P13501
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	VLST-002, VLST002, VLST002
背景	C-C motif chemokine 5 (CCL5/RANTES) is a ~9 kDa protein. Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). 1. Kameyoshi, Y. et al. (1992) The Journal of experimental medicine 176, 587-92. PMID: 1380064 2. Lim, JK. et al. (2005) Journal of leukocyte biology 78, 442-52. PMID: 15923218 3. Capoulade-Métay, C. et al. (2006) Immunogenetics 58, 533-41. PMID: 16791620 4. Cocchi, F. et al. (1995) Science (New York, N.Y.) 270, 1811-5. PMID: 8525373 5. Proost, P. et al. (1998) The Journal of biological chemistry 273, 7222-7. PMID: 9516414 6. Liu, B. et al. (2013) Diabetologia 56, 2467-76. PMID: 23979485
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10) (HV080407) Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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SDS-PAGE for Research Grade Anti-Human CCL5/RANTES Antibody (VLST-002)

参考文献

データシート

Anti-Human CCL5/RANTES Reference Antibody (VLST-002, RUO).pdf

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Anti-Human CCL5/RANTES Reference Antibody (VLST-002, RUO) (HY346026)

概要

イメージ

参考文献

データシート

SDS

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