Anti-Human CD131/CSF2RB Reference Antibody (CSL 311, RUO) (HW498016)

Name: Anti-Human CD131/CSF2RB Reference Antibody (CSL 311, RUO)
Brand: abinScience
SKU: HW498016
Price: 370 USD
Availability: InStock

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Numéro de catalogue	HW498016
Description	Anti-Human CD131/CSF2RB (CSL 311) (HW498016) is a research-grade recombinant antibody targeting CD131. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG
ID de clone	CSL 311
Système d'expression	Mammalian cells
Nature	Recombinant
Cible	Cytokine receptor common subunit beta, IL3RB, IL5RB, CDw131, CD131, CSF2RB, GM-CSF/IL-3/IL-5 receptor common beta subunit
Niveau d'endotoxines	< 10 EU/mg as determined by LAL method.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P32927
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	CSL-311, CSL311, CSL311
Contexte	Cytokine receptor common subunit beta (CD131/CSF2RB) is a ~97 kDa protein. Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Acts by forming an heterodimeric receptor through interaction with different partners such as IL3RA, IL5RA or CSF2RA. In turn, participates in various signaling pathways including interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor/CSF2 pathways. In unstimulated conditions, interacts constitutively with JAK1 and ligand binding leads to JAK1 stimulation and subsequent activation of the JAK-STAT pathway. 1. Tavernier, J. et al. (1992) Proceedings of the National Academy of Sciences of the United States of America 89, 7041-5. PMID: 1495999 2. Ogata, N. et al. (1998) Blood 91, 2264-71. PMID: 9516124
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human CD131/CSF2RB (CSL 311)

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Anti-Human CD131/CSF2RB Reference Antibody (CSL 311, RUO).pdf

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Anti-Human CD131/CSF2RB Reference Antibody (CSL 311, RUO) (HW498016)

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