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Anti-Human EMMPRIN/CD147 Reference Antibody (SAA0324, RUO) (HW664013)

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Anti-Human EMMPRIN/CD147 Reference Antibody (SAA0324, RUO)
Anti-Human EMMPRIN/CD147 Reference Antibody (SAA0324, RUO)
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Vista general
Número de catálogoHW664013
Descripción
Anti-Human CD147/BSG (SAA0324) (HW664013) is a research-grade recombinant antibody targeting CD147.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
Reactividad de especiesHuman
AplicacionesELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huéspedChimeric
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clonSAA0324
Sistema de expresión Mammalian cells
Naturaleza Recombinant
Objetivo Hepatoma-associated antigen, BSG, HAb18G, 5F7, TCSF, OK blood group antigen, Collagenase stimulatory factor, CD147, Leukocyte activation antigen M6, Basigin, Extracellular matrix metalloproteinase inducer, EMMPRIN, Tumor cell-derived collagenase stimulatory factor
Nivel de endotoxinas < 10 EU/mg as determined by LAL method.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P35613
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Basigin (CD147/BSG) is a ~42 kDa protein. Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes.

1. Aït-Ali, N. et al. (2015) Cell 161, 817-32. PMID: 25957687
2. Redzic, JS. et al. (2011) Journal of molecular biology 411, 68-82. PMID: 21620857
Nota For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Imágenes
  • Anti-Human EMMPRIN/CD147 Reference Antibody (SAA0324, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CD147/BSG (SAA0324).

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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