Anti-Human CD160 Reference Antibody (MAT 303, RUO) (HF985016)

Name: Anti-Human CD160 Reference Antibody (MAT 303, RUO)
Brand: abinScience
SKU: HF985016
Price: 370 USD
Availability: InStock

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100ug
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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HF985016

Description

Anti-Human CD160 (MAT 303) (HF985016) is a research-grade recombinant antibody targeting CD160. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Reactivité des espèces

Human

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

IgG

ID de clone

MAT 303

Système d'expression

Mammalian cells

Cible

Natural killer cell receptor BY55, CD160 antigen, CD160, BY55

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

O95971

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Noms alternatifs

MAT-303, MAT303, MAT303

Contexte

CD160 antigen is a ~19 kDa protein. Receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta chain in activated T cells. Receptor for both classical and non-classical MHC class I molecules. In the context of acute viral infection, recognizes HLA-C and triggers NK cell cytotoxic activity, likely playing a role in anti-viral innate immune response. On CD8+ T cells, binds HLA-A2-B2M in complex with a viral peptide and provides a costimulatory signal to activated/memory T cells.

1. Nikolova, M. et al. (2002) International immunology 14, 445-51. PMID: 11978774

2. Rabot, M. et al. (2007) International immunology 19, 401-9. PMID: 17307798

3. Giustiniani, J. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 182, 63-71. PMID: 19109136

4. Le Bouteiller, P. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 16963-8. PMID: 12486241

5. Agrawal, S. et al. (1999) Journal of immunology (Baltimore, Md. : 1950) 162, 1223-6. PMID: 9973372

6. Viganò, S. et al. (2014) PLoS pathogens 10, e1004380. PMID: 25255144

7. Fons, P. et al. (2006) Blood 108, 2608-15. PMID: 16809620

8. Cai, G. et al. (2008) Nature immunology 9, 176-85. PMID: 18193050

Note

For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD160 (MAT 303)

Reférences

Fiche technique

Anti-Human CD160 Reference Antibody (MAT 303, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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